In late 1968 Ferrari replaced the 330 GTC with the 365 GTC. The new model was in fact a re-engine of the 330 GTC, featuring almost the same design. Differences were limited to non-vented front fenders and a vented hood. Until 1970, when the car was discontinued Ferrari produced 168 units, in both left hand and right hand drive configuration.
Like the 330 GTC models, the bodies were built at the Pininfarina works in Turin, then delivered fully trimmed to Ferrari for fitments of the mechanical components.
The 365 GTC was built on a 2400mm wheelbase tubular steel chassis with the layout virtually identical to that of the models replaced, as the only mechanical change that had occurred was in the size of the engine. The standard road wheels were the ten-hole alloy design, as fitted to their predecessor, whilst similarly Borrani wire wheels were available as an option.
The 365 GTC featured an enlarged version of the engine used in the 330 GTC: a 4,4 liter V12 engine with a bore and stroke of 81mm x 71mm. It was fitted with a bank of either three twin-choke Weber 40 DFI/5 or 40 DFI/7 carburettors, with a twin coil and rear-of-engine mounted twin distributor ignition system.
The engine was delivering 320 hp and was mated to a five-speed transaxle transmission.
In 2008 a Ferrari 365 GTC was auctioned by RM Auctions for a bid of $324,500.